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Optimizing the treatment of joints affected by rheumatoid arthritis

Optimising the treatment of joints affected by rheumatoid arthritis was the subject of a systematic study by the V. Kumar (2005). The effects of differently set pulsed magnetic fields were compared in an animal model.

By using a factorial design (one-to-one), this study was able to determine the most optimal combination of frequency, intensity and duration of treatment for sinusoidal pulsed magnetic field waves.

Pulsed magnet therapy with 5 Hz and 4 µT parameters and a duration of 90 minutes proved to be the most effective for reducing swelling and slowing down the decomposition of the surrounding tissue by reducing the activity of lysosomal enzymes.

With increased lysosomal activity, there is usually more degradation of some proteins. Specifically, in rheumatoid arthritis and other chronic inflammatory diseases, lysosomal enzymes can enter the extracellular space and degrade surrounding tissues.

The reduction of soft tissue swelling in this study was confirmed by radiological examination. The results of the histological examination further confirmed a decrease in inflammatory cells and, in contrast, a multiplication and increase in the volume of cells inside the joint (hyperplasia and hypertrophy of cells surrounding the synovial membrane).

According to the study, pulsed magnet therapy has a stabilising effect on the tissue lining the inside of the joint and is therefore a suitable treatment for patients whose joints are affected by rheumatoid arthritis.

Source: Kumar, V. et al. (2005) Optimization of pulsed electromagnetic field therapy for management of arthritis in rats. Bioelectromagnetics, 26(6), 431-439.

Optimalizace pulzní magnetoterapie pro zvládání arritidy u krys / Optimization of pulsed electromagnetic field therapy for management of arthritis in rats

http://www.ncbi.nlm.nih.gov/pubmed/15887257

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