Action on the mechanisms of blood vessel formation

Effects on the mechanisms of vessel formation after application of a low-frequency pulsed electromagnetic field with a frequency of 30 Hz and an intensity of 5 mT. These mechanisms and effects in an animal model were thoroughly described in a study (Li et al.) published in 2015.

This study not only investigated whether pulsed magnetotherapy would promote blood vessel formation, but also further studied the underlying fundamental cellular and molecular mechanisms.

After two weeks of daily applications, the pulsed electromagnetic field increased the levels of vascular endothelial growth factor (VEGF) and endothelial nitric oxide synthesis (eNOS), resulting in an overall improvement in the formation of new blood capillaries (angiogenesis).

The results of the study clearly demonstrated that low-frequency pulsed magnet therapy significantly accelerates healing, reduces the spread of dead tissue (gangrene) and improves new blood vessel formation (neovascularization).

Pulsed magnet therapy is therefore suitable for the treatment of critical limb ischemia.

Source: Li, R.-L. et al. (2015) Pulsed electromagnetic field improves postnatal neovascularization in response to hindlimb ischemia. American Journal of Translational Research. 7 (3), 430-444.

Pulzní elektromagnetické pole improves postnatal neovascularization in response to hindlimb ischemia / Pulsed electromagnetic field improves postnatal neovascularization in response to hindlimb ischemia

http://www.ncbi.nlm.nih.gov/pubmed/26045885

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